diff --git a/docs/examples/r2.md b/docs/examples/r2.md
index ecbb8150..e20d1888 100644
--- a/docs/examples/r2.md
+++ b/docs/examples/r2.md
@@ -22,7 +22,7 @@ It's easy to read and write data to and from Cloudflare R2 with obstore's [`S3St
     access_key_id = "..."
     secret_access_key = "..."
     store = S3Store.from_url(
-        "https://f0b62eebfbdde1133378bfe3958325f6.r2.cloudflarestorage.com/ kylebarron-public",
+        "https://f0b62eebfbdde1133378bfe3958325f6.r2.cloudflarestorage.com/kylebarron-public",
         access_key_id=access_key_id,
         secret_access_key=secret_access_key,
     )
@@ -37,7 +37,7 @@ It's easy to read and write data to and from Cloudflare R2 with obstore's [`S3St
     access_key_id = "..."
     secret_access_key = "..."
     bucket = "kylebarron-public"
-    endpoint = "https://f0b62eebfbdde1133378bfe3958325f6.r2.cloudflarestorage. com"
+    endpoint = "https://f0b62eebfbdde1133378bfe3958325f6.r2.cloudflarestorage.com"
     store = S3Store(
         bucket,
         access_key_id=access_key_id,
diff --git a/pyo3-object_store/src/aws/store.rs b/pyo3-object_store/src/aws/store.rs
index f8041c4a..93b6fc55 100644
--- a/pyo3-object_store/src/aws/store.rs
+++ b/pyo3-object_store/src/aws/store.rs
@@ -413,6 +413,16 @@ fn parse_url(
                     config.insert_if_not_exists(AmazonS3ConfigKey::Bucket, bucket);
                 }
             }
+            Some((account, jurisdiction, "r2", "cloudflarestorage.com")) => {
+                config.insert_if_not_exists(AmazonS3ConfigKey::Region, "auto");
+                let endpoint = format!("https://{account}.{jurisdiction}.r2.cloudflarestorage.com");
+                config.insert_if_not_exists(AmazonS3ConfigKey::Endpoint, endpoint);
+
+                let bucket = parsed.path_segments().into_iter().flatten().next();
+                if let Some(bucket) = bucket {
+                    config.insert_if_not_exists(AmazonS3ConfigKey::Bucket, bucket);
+                }
+            }
             _ => {
                 return Err(ParseUrlError::UrlNotRecognised {
                     url: parsed.as_str().to_string(),
diff --git a/tests/store/test_s3.py b/tests/store/test_s3.py
index dd9061f2..4864f75c 100644
--- a/tests/store/test_s3.py
+++ b/tests/store/test_s3.py
@@ -75,6 +75,20 @@ async def test_from_url():
     _meta = await store.head_async("2024-01-01_performance_fixed_tiles.parquet")
 
 
+@pytest.mark.parametrize(
+    "url",
+    [
+        "https://account.r2.cloudflarestorage.com/bucket",
+        "https://account.eu.r2.cloudflarestorage.com/bucket",
+    ],
+)
+def test_r2_from_url(url: str):
+    store = S3Store.from_url(url)
+    endpoint = store.config.get("endpoint")
+    assert endpoint is not None
+    assert (".eu." in endpoint) == (".eu." in url)
+
+
 def test_pickle():
     store = S3Store(
         "ookla-open-data",