diff --git a/pyproject.toml b/pyproject.toml
index 18a1e88..1498936 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -31,8 +31,8 @@ keywords = [
 requires-python = ">=3.10"
 dynamic = ["version"]
 dependencies = [
-    "ga4gh.vrs>=2.2.0,<3.0",
-    "ga4gh.cat_vrs~=0.7.1",
+    "ga4gh.vrs~=2.4.0a0",
+    "ga4gh.cat_vrs~=0.8.0a0",
     "pydantic>=2.0,<3.0",
     "typing_extensions",
 ]