Issues

• Segfault in CudaCustomAllocator::_free during GPU refinement, possibly related to #1369 (exact-fit reuse of blocks still marked for deferred free)

  3dem/relion#1374 · Filter by author uermel opened on Oct 2, 2026

• The tomogram reconstructed by RELION5 contains artifacts

  3dem/relion#1373 · Filter by author abnerabner opened on Sep 29, 2026

• Is it possible to install the tomography_python_programs for an existing Relion 5.0.1 installation?

  3dem/relion#1370 · Filter by author samfux84 opened on Sep 28, 2026

• The sum of weights for all orientations was found to be zero

  3dem/relion#1366 · Filter by author lpit1 opened on Aug 27, 2026

• Python dependency clarification

  3dem/relion#1341 · Filter by author FlyinTeller opened on Apr 21, 2026
  5

• feature request regarding gold bead removal and generation of final aligned stack in imod tab

  3dem/relion#1339 · Filter by author Ankushcreatedroid opened on Apr 2, 2026

• RELION --tomo job Align

  3dem/relion#1337 · Filter by author larsonmattr opened on Mar 27, 2026

• No orientation was found as better than any other

  3dem/relion#1336 · Filter by author FelixGersteuer opened on Mar 26, 2026

• Creating Relion-5 compatible star files (particle and tomogram) from Warp to re-extract particles with Relion

  3dem/relion#1333 · Filter by author mpm896 opened on Mar 19, 2026
  4

• Relion-5.1: Pick tomograms error: "ModuleNotFoundError: No module named 'pydantic._internal'"

  3dem/relion#1332 · Filter by author suistem opened on Mar 19, 2026
  4

• Compilation error with pre-release 5.1.0

  3dem/relion#1331 · Filter by author multimeric opened on Mar 17, 2026
  2

• AlignTiltSeries aligned_tilt_series.star file always reports rlnIMODLeaveOutError as 0

  3dem/relion#1328 · Filter by author JadisInka opened on Feb 20, 2026

• Incorrect Import tilt_series star files if mdoc directory contains duplicate mdocs

  3dem/relion#1327 · Filter by author JadisInka opened on Feb 13, 2026

• Installation failed during the make step filing to download fltk-1.3.5-source.tar.gz

  3dem/relion#1326 · Filter by author bpavie opened on Jan 22, 2026
  1

• --failsafe_threshold in ml_optimiser is no longer used.

  3dem/relion#1325 · Filter by author huwjenkins opened on Jan 16, 2026
  1

• 3D classification in RELION.

  3dem/relion#1324 · Filter by author chlamydomonas-move opened on Jan 16, 2026
  3

• AssertionError: Unknown attribute fp32_precision

  3dem/relion#1322 · Filter by author KunFang93 opened on Jan 8, 2026
  10

• A bug related to the process of doing Polish after using Motioncor3

  3dem/relion#1321 · Filter by author hunkui1 opened on Jan 6, 2026
  6

• Can Polish jobs be continued?

  3dem/relion#1320 · Filter by author Phaips opened on Jan 2, 2026
  4

• MultiBody MPI send/receive buffer size mismatch

  3dem/relion#1319 · Filter by author fullerjamesr opened on Dec 18, 2025
  1

• Inconsistent GPU utilization in 3D auto-refine with 4 GPUs (0:1:2:3)

  3dem/relion#1318 · Filter by author frootloopgkw opened on Dec 12, 2025
  1

• Napari crash on close

  3dem/relion#1316 · Filter by author mapaulson opened on Nov 28, 2025
  1

• Refine3D crashes after first iteration with duplicate helical segment error

  3dem/relion#1312 · Filter by author kg19823 opened on Oct 27, 2025
  1

• Problems compiling and running

  3dem/relion#1311 · Filter by author ejames604 opened on Oct 27, 2025
  1

• GPUs not being parallelised and CPU being favoured

  3dem/relion#1310 · Filter by author KubaWEM opened on Oct 24, 2025
  11