Version: 2.3.0 beta
Release date: 5 October 2015
Server' website: http://mgra.cblab.org/ (decomissioned)
MGRA (Multiple Genome Rearrangements and Ancestors) - a tool for reconstruction of ancestral gene orders and the history of genome rearrangements for multiple input genomes.
See docs/INSTALL.md file.
See docs/USAGE.md file.
- Pavel Avdeyev (University of Texas Southwestern Medical Center, TX)
- Nikita Kartashov (Academic University, St. Petersburg, Russia)
- Shuai Jiang (University of South Carolina)
- Max Alekseyev (The George Washington University, Washington, DC)
- P. Avdeyev, S. Jiang, S. Aganezov, F. Hu, and M. A. Alekseyev. "Reconstruction of ancestral genomes in presence of gene gain and loss". Journal of Computational Biology 23:3 (2016), 150–164. doi:10.1089/cmb.2015.0160 bioRxiv:10.1101/040196
- M. A. Alekseyev and P. A. Pevzner. "Breakpoint Graphs and Ancestral Genome Reconstructions". Genome Research 19(5) (2009), pp. 943-957
- P. Avdeyev, S. Jiang, and M. A. Alekseyev. "Linearization of Median Genomes under the Double-Cut-and-Join-Indel Model". Evolutionary Bioinformatics 15 (2019), 1–12. doi:10.1177/1176934318820534
You can send your feedback to Max Alekseyev maxal@gwu.edu
You also can report bugs or suggest features using issue tracker at GitHub https://github.com/ablab/mgra/issues
The work was supported by National Science Foundation under the grant No IIS-1253614.
We would like to thank:
- Nadiya Sitdykova
- Aleksey Gurevich (testing and some useful suggestions)
MGRA is distributed under GNU GPL v2 license, see LICENSE.
It also uses third-party librarires and programs:
- Blossom V (see src/libs/blossom5/LICENSE.TXT), author Vladimir Kolmogorov
http://pub.ist.ac.at/~vnk/software.html#BLOSSOM5
- Boost (Boost Software License)