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Pfam review: 16 owner-classified rows, specificity notes, owner decisions Q6-Q8, R0 status for C. albicans - #73
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… for composite calls Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
…heet Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
…the open rows Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
…sheet complete Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
…tivated) Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
…no family activated Notes follow the owner review of 2026-10-07 (16 rows) and the counts in docs/reports/2026-10-07-pfam-specificity-notes-draft.md. active stays no for all 15 families. Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
Owner sign-off 2026-10-07 after the specificity review (8 rows classified, 25 of 29 hits are glycoside hydrolase or fragment false hits removed by the signal_peptide condition; the 4 hits that pass are S. cerevisiae FLO1, FLO5, FLO9, FLO10). With PA14 active: S288C 4 hits, Af293 0. Status stays unvalidated. The shipped-table test now pins the signed-off set. Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com>
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What this adds
Follow-up to #72 (merged before these commits were pushed). 15 commits.
uncharacterised_true_member, PA14 8 arefalse_domain_hit. Sheet:docs/reports/data/sorting_hat/specificity/review_sheet_first_signoff.tsv, with PredGPI calls, Af293 ortholog columns,n_tm_mature, and a full Pfam-A scan of the open rows (open10.pfamA_scan.domtbl). Each row's note records the owner's reasoning and caveats.data/sorting_hat/family_table.tsv: threespecificity_noteedits (CFEM, PA14, Hydrophobin).activeisnofor all 15 families. Nothing is activated. The change is its own commit (8b1692b). Draft and consequences:docs/reports/2026-10-07-pfam-specificity-notes-draft.md.docs/paper/03decision 3 corrected (composite calls report a derived status) anddocs/paper/04updated.smoke, sensitivity 0.477 [0.356, 0.591]); report and handoff updated.Read before merging
active = yesis the owner's separate change, committed alone, per Plan 2.pfam_proposals.pyfrom table facts. The member lists are drafts. The notes state counts, not sensitivity or specificity.no_tmdoes not remove it).maindiffers from this branch only by the merge commit of Pfam proposals, CGD curation leads, owner decisions, per-call status spec (grilling session 2026-10-07) #72.Package tests: 683 passed, 7 skipped (shellcheck absent). Pre-commit (ruff, ruff-format) passes. No code changed except analysis scripts already in #72.
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