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Pfam proposals, CGD curation leads, owner decisions, per-call status spec (grilling session 2026-10-07) - #72
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…all status spec, verification, handoff - Pfam proposals for 122 hits in 6 proteomes (status proposed; no family set active) - CGD biofilm and cell wall literature leads; RBT1 evidence; owner_decisions.tsv for Q6FTA2 and Q59TP1 - R0 status source added to the two S288C runs; FLO11 repeat miss explained - Spec for per-call status entries (draft, not reviewed) - Verification of YPS3, BcLysM1, WHO/IUIS counts and table B3 - Handoff of 2026-10-07 Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
Review (Opus, read-only): needs rework. Two blockers and eight majors applied; owner questions Q6 to Q8 marked. Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
…roposals for 159 hits in 8 proteomes The Phase C C. albicans FASTA has 38 duplicate IDs with identical sequences; a deduplicated copy was used. HWP1, HWP2 and EAP1 have no hit from any of the 15 models. Co-Authored-By: Claude Sonnet 5.5 <noreply@anthropic.com> Claude-Session: https://claude.ai/code/session_01JXibAde2qW2uRZ4pShs1sW
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What this adds
Output of the owner grilling session of 2026-10-07. Handoff:
docs/HANDOFF-2026-10-07.md(decisions 1 to 12 are in section 2).proposed(docs/reports/data/sorting_hat/specificity/pfam_proposals.tsv,analysis/sorting_hat_run/pfam_proposals.py). Family-level proposal:docs/reports/2026-10-07-pfam-family-proposals.md. No family is setactive.data/sorting_hat/family_table.tsvis unchanged.owner_decisions.tsv, adjudication README). RBT1 keeps its adhesin E2 label with PMIDs 10978273, 19837954, 21414038. Braun 2000 was read: the two RBT1 alleles differ by a segment (aa 612 to 640), not by repeat number.smoke). Report and run copies updated.analysis/cocci_repeats/REPORT_2026-09-30_pfam_confirmation.mdis not supported by this measurement; that file is not changed.docs/curation-leads/,data/curated/biofilm/cgd_biofilm_literature_leads.tsv,cgd_adherence_literature_leads.tsv.docs/superpowers/specs/2026-10-07-per-call-status-design.md). Draft. No independent review yet and no code.docs/paper/02(24 values matchmetrics.json; the B1 cell for A. nidulans is filled).Read before merging
needs_expert.docs/paper/02.Pre-commit (ruff 0.3.5 and ruff-format) passes.
pfam_proposals.pyreproduces the stored TSV exactly. No test was added: the scripts are analysis scripts.🤖 Generated with Claude Code